What is the role of free radical scavengers in acute stroke?
نویسندگان
چکیده
منابع مشابه
Quantitative Structure Activity Relationship Analysis of Coumarins as Free Radical Scavengers by Genetic Function Algorithm
The antioxidant properties of coumarin derivatives using the 2,2ˈ -diphenyl-1- picrylhydrazyl (DPPH) radical scavenging assay were investigated by the application of Quantitative Structure Activity Relationship (QSAR) studies. The molecular structures were optimized and submitted for the generation of quantum chemical and molecular descriptors. Genetic Function Algorithm (GFA) was employed in m...
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references 1. Hatwalne MS. Free radical scavengers in anaesthesiology and critical care. Indian J Anaesth 2012;56:227‐33. 2. Pham‐Huy LA, He H, Pham‐Huy C. Free radicals, antioxidants in disease and health. Int J Biomed Sci 2008;4:89‐96. 3. Kikuchi K, Miura N, Kawahara KI, Murai Y, Morioka M, Lapchak PA, et al. Edaravone (Radicut), a free radical scavenger, is a potentially useful addition to t...
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Efficacious treatment of acute stroke is a major challenge in modern medicine. Therapeutic neuroprotection acting towards minimization of ischemic neuronal injury in penumbral tissue in the regions of reduced cerebral blood flow seems to be an appealing concept in the treatment of acute stroke and brain trauma. The ‘ischemic cascade’, a complex mechanism of metabolic events initiated by brain i...
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ورودعنوان ژورنال:
- JPMA. The Journal of the Pakistan Medical Association
دوره 62 5 شماره
صفحات -
تاریخ انتشار 2012